Melperone (hydrochloride), CAS 1622-79-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone, monohydrochloride

Purity: ≥98%

Formula Markup: C16H22FNO / HCl

Formula Weight: 299.8

CAS Number: 1622-79-3

Notes: Melperone is an atypical antipsychotic.{25511} It binds to α1- and α2-adrenergic and dopamine D2 receptors (Kds = 180, 150, and 180 nM, respectively), as well as the serotonin (5-HT) receptor subtype 5-HT2A (Kd = 102 nM). It is selective for these receptors over histamine H1, muscarinic, 5-HT1A, 5-HT1D, and 5-HT2C receptors (Kds = 580, >10,000, 2,200, 3,400, and 2,100 nM, respectively). Melperone (2 mg/kg per day) increases basal, but not amphetamine-induced, extracellular dopamine levels in the rat nucleus accumbens.{53986}

• SKU: CAY19770-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19770-10
• Package Unit: 10 mg
• Quantity Unit: STK