Mepazine (hydrochloride), CAS 2975-36-2

Product Description: Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine hydrochloride affects viability of ABC-DLBCL cells by enhancing apoptosis[1].

Applications: Cancer-programmed cell death

Formula: C19H23ClN2S

References: [1]Nagel D, et al. Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL. Cancer Cell. 2012 Dec 11;22(6):825-37.

CAS Number: 2975-36-2

Molecular Weight: 346.92

Compound Purity: 99.94

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 2.22 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;MALT1

• SKU: MEXHY-121282A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121282A-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK