Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-1,2-ethanediamine, 2Z-butenedioate
Purity: ≥95%
Formula Markup: C17H23N3O / C4H4O4
Formula Weight: 401.4563
CAS Number: 59-33-6
Notes: Mepyramine is a first generation antihistamine that acts as an inverse agonist at the histamine H1 receptor. It is reported to bind with high affinity to a Gq/11 protein-coupled form of the receptor and to promote a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling of the endogenously expressed receptor, as well as to reduce G protein availability for other non-related receptors associated with this signaling pathway.{32838} Mepyramine has been shown to inhibit histamine-induced inositol phosphate production with a log EC50 value of -7.94.{32838}
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