Product Description: Mequinol (4-Methoxyphenol)yes MercurialisOne of the bioactive ingredients, mainly used for skin discoloration[1]. MequinolIs an antioxidant that has additive/synergistic effects on carcinogenesis when combined with other phenolic antioxidants. Mequinolalso promote hERαDependent chaperone production with potential estrogenic activity[1][2][3].
Formula: C7H8O2
References: [1]Callender VD, et al. Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. Am J Clin Dermatol. 2011 Apr 1;12(2):87-99./[2]Kita K, et al. Increase in the levels of chaperone proteins by exposure to beta-estradiol, bisphenol A and 4-methoxyphenol in human cells transfected with estrogen receptor alpha cDNA. Toxicol In Vitro. 2009 Jun;23(4):728-35./[3]Hirose M, et al. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. Carcinogenesis. 1998 Jan;19(1):207-12.
CAS Number: 150-76-5
Molecular Weight: 124.139
Compound Purity: 99.98
Research Area: Endocrinology
Solubility: DMSO : ≥ 100 mg/mL/H2O : ≥ 100 mg/mL
Target: Estrogen Receptor/ERR;HSP