Shelf life (days): 730.0
Formulation: A solution in methyl acetate
Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenyl-phosphonofluoridic acid, methyl ester
Purity: ≥98%
Formula Markup: C21H36FO2P
Formula Weight: 370.5
CAS Number: 188404-10-6
Notes: Methyl arachidonyl fluorophosphonate (MAFP) is an inhibitor of monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH; IC50s = 26 and 0.33 nM, respectively).{53947} It is also an irreversible inhibitor of cytosolic phospholipase A2 (cPLA2), as well as calcium-independent PLA2 (iPLA2; IC50 = 500 nM).{2494,2989,2302} MAFP inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 600 nM.{2494}