Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3,4,5-trihydroxy-benzoic acid, methyl ester
Purity: ≥98%
Formula Markup: C8H8O5
Formula Weight: 184.1
CAS Number: 99-24-1
Notes: Methyl gallate is a phenol that has been found in Meliaceae and has diverse biological activities.{61066,61081,32922,31596} It reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells when used at a concentration of 50 µM.{61066} Methyl gallate is active against V. cholerae in vitro (MIC = 32 µg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice when administered at doses of 50, 100, and 200 mg/kg.{61081} It reduces tumor growth and decreases the number of intratumor CD25+Foxp3high regulatory T cells (Tregs) in an EL-4 model of murine lymphoma.{32922} Methyl gallate (0.7, 7, and 70 mg/kg) reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis.{31596}
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