Product Description: Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury[1][2][3][4].
Applications: COVID-19-immunoregulation
Formula: C8H8O3
References: [1]Soni MG, et al. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002 Oct;40(10):1335-73./[2]Elmore SE, et al. Disruption of normal adipocyte development and function by methyl- and propyl- paraben exposure. Toxicol Lett. 2020 Nov 1;334:27-35./[3]Kopalli SR, et al. Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease. Neurotoxicology. 2013 Jan;34:25-32./[4]Gal A, et al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106./[5]Elmore SE, et al. Disruption of normal adipocyte development and function by methyl- and propyl- paraben exposure. Toxicol Lett. 2020 Nov 1;334:27-35./[6]Gal A, et al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106./[7]Kopalli SR, et al. Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease. Neurotoxicology. 2013 Jan;34:25-32.
CAS Number: 99-76-3
Molecular Weight: 152.15
Compound Purity: 99.99
Research Area: Infection; Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Bacterial;Endogenous Metabolite
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