Microcolin H, CAS 2408008-21-7

Product Description: Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].

Applications: Cancer-programmed cell death

Formula: C38H63N5O9

References: [1]Yang H et al. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduct Target Ther. 2023 Nov 15;8(1):428.

CAS Number: 2408008-21-7

Molecular Weight: 733.93

Compound Purity: 99.05

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Atg8/LC3;Autophagy;p62

• SKU: MEXHY-163001-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163001-5
• Package Unit: 5 mg
• Quantity Unit: STK