Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 6-(1-piperidinyl)-2,4-pyrimidinediamine 3-oxide
Purity: ≥98%
Formula Markup: C9H15N5O
Formula Weight: 209.3
CAS Number: 38304-91-5
Notes: Minoxidil is a pyrimidine derivative that was originally developed as an anti-hypertensive agent and unexpectedly found to stimulate hair growth. Minoxidil directly affects arteriolar smooth muscle to decrease vascular resistance in part by opening ATP-sensitive potassium channels.{24983,24984} It can activate cyclooxygenase 1 (AC50 = 80 μM), which is expressed in the dermal papilla of hair follicles, increasing prostaglandin E2 production in BALB/c 3T3 fibroblasts and human dermal papilla fibroblasts.{4171}