MK-3207, CAS 957118-49-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 8R-(3,5-difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide

Purity: ≥98%

Formula Markup: C31H29F2N5O3

Formula Weight: 557.6

CAS Number: 957118-49-9

Notes: A CGRP receptor antagonist (Ki = 22 pM for the recombinant human receptor); selective for the CGRP receptor over the AM1 and AM2 receptors, CT receptor, and AMY3 receptor (Kis = 16.5, 0.156, 1.9, and 0.128 µM, respectively) but does inhibit the AMY1 receptor to a lesser extent (Ki = 750 pM); inhibits CGRP-induced cAMP production in HEK293 cells expressing the human CGRP receptor (IC50 = 120 pM); decreases capsaicin-induced forearm dermal vasodilation in rhesus monkeys

• SKU: CAY42490-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42490-1
• Package Unit: 1 mg
• Quantity Unit: STK