MK-8745, CAS 885325-71-3

Product Description: MK-8745 is an aurora A kinase inhibitor with an IC50 of 0.6 nM.

Applications: Cancer-Kinase/protease

Formula: C20H19ClFN5OS

References: [1]Jayasree S Nair et al. The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent./[2]Aparajita Chowdhury et al. A novel Aurora kinase A inhibitor MK-8745 predicts TPX2 as a therapeutic biomarker in non-Hodgkin lymphoma cell lines. Leuk Lymphoma, 2012 Mar, 53(3):462-71.

CAS Number: 885325-71-3

Molecular Weight: 431.91

Compound Purity: 99.49

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Apoptosis;Aurora Kinase

• SKU: MEXHY-13819-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13819-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK