Shelf life (days): 1460.0
Formulation: A solid
Formal Name: rel-3-(1,3-benzodioxol-5-yl)-1-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone
Purity: ≥98%
Formula Markup: C25H31NO6
Formula Weight: 441.51678
CAS Number: 1334526-14-5
Notes: ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50 = 1.1 µM in a reporter assay).{53859} It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50 = 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated naïve cord blood human CD4+ T cells into Th17 T helper cells.