ML-239, CAS 1378872-36-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-(2,4,6-trichlorophenoxy)-acetic acid, (2E)-2-(1H-pyrrol-2-ylmethylene)hydrazide

Purity: ≥98%

Formula Markup: C13H10Cl3N3O2

Formula Weight: 346.6

CAS Number: 1378872-36-6

Notes: ML-239 is an inhibitor of cancer stem cells, displaying greater than 23-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 1.18 µM) over an isogenic control cell line (EC50 = 27.6 µM).{24522,24523,24524} It is also toxic to the breast carcinoma cell line MDA-MB-231.{24522} ML-239 alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways.{24522,24524} It is stable in saline and modestly stable in human plasma.{24523}

• SKU: CAY15188-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15188-25
• Package Unit: 25 mg
• Quantity Unit: STK