ML-323, CAS 1572414-83-5

Product Description: ML-323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay. The measured inhibition constants of ML-323 for the free enzyme (Ki) is 68 nM.

Applications: Cancer-programmed cell death

Formula: C23H24N6

References: [1]Liang Q, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014 Apr;10(4):298-304./[2]Dexheimer TS, et al. Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex. National Center for Biotechnology Information; 2010-2012 Oct 23.

CAS Number: 1572414-83-5

Molecular Weight: 384.48

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : ≥ 49 mg/mL

Target: Deubiquitinase

• SKU: MEXHY-17543-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17543-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK