Product Description: ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity[1].
Applications: COVID-19-anti-virus
Formula: C26H31N3O3
References: [1]Jacobs J, et al. Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. J Med Chem. 2013 Jan 24;56(2):534-46.
CAS Number: 1417700-13-0
Molecular Weight: 433.54
Compound Purity: 99.87
Research Area: Infection
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: SARS-CoV;Virus Protease