MLN8054, CAS 869363-13-3

Product Description: MLN8054 is a potent, selective and orally available aurora A kinase inhibitor with an IC50 of 4 nM.

Applications: Cancer-Kinase/protease

Formula: C25H15ClF2N4O2

References: [1]Manfredi MG, et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4106-11./[2]Huck JJ, et al. MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo. Mol Cancer Res. 2010 Mar;8(3):373-84.

CAS Number: 869363-13-3

Molecular Weight: 476.86

Compound Purity: 99.54

Research Area: Cancer

Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Aurora Kinase

• SKU: MEXHY-10180-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10180-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK