Product Description: MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM[1].
Applications: COVID-19-immunoregulation
Formula: C19H19Cl2N9O3
References: [1]Quancard J, et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Mar;15(3):304-313.
CAS Number: 1832578-30-9
Molecular Weight: 492.32
Compound Purity: 99.89
Research Area: Inflammation/Immunology
Solubility: DMSO : 200 mg/mL (ultrasonic)
Target: MALT1