Clone Name: 4C21
Application Note: WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 30
Specificity/Sensitivity: This antibody recognizes human MMP-7 in western blot without cross reactivity with other human MMPs.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Uniprot ID: P09237
Antigen Species: Human
Immunogen: Human recombinant MMP-7
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: matrix metallopeptidase 7
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