MMV390048, CAS 1314883-11-8

Product Description: MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent[1].

Applications: COVID-19-immunoregulation

Formula: C18H14F3N3O2S

References: [1]Paquet T, et al. Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Sci Transl Med. 2017 Apr 26;9(387). pii: eaad9735.

CAS Number: 1314883-11-8

Molecular Weight: 393.38

Compound Purity: 99.17

Research Area: Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Parasite;PI4K

• SKU: MEXHY-106005-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106005-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK