Molibresib, CAS 1260907-17-2

Product Description: Molibresib (I-BET762; GSK525762) is a BET bromodomain inhibitor with IC50 of 32.5-42.5 nM.

Applications: Cancer-programmed cell death

Formula: C22H22ClN5O2

References: [1]Nicodeme E, et al. Suppression of inflammation by a synthetic histone mimic. Nature. 2010 Dec 23;468(7327):1119-23./[2]Asangani IA, et al. Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer. Nature. 2014 Jun 12;510(7504):278-82./[3]Chaidos A, et al. Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762. Blood. 2014 Jan 30;123(5):697-705.

CAS Number: 1260907-17-2

Molecular Weight: 423.90

Compound Purity: 99.94

Research Area: Cancer

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain

• SKU: MEXHY-13032-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13032-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK