Monomethyl auristatin E intermediate-2

Product Description: Monomethyl auristatin E intermediate-2 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Applications: Cancer-programmed cell death

Formula: C15H27NO6

References: [1]Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Molecular Weight: 317.382

Compound Purity: 97.54

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-49413-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-49413-100
• Package Unit: 100 mg
• Quantity Unit: STK