Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-(6-hydroxy-2-benzofuranyl)-1,3-benzenediol
Purity: ≥98%
Formula Markup: C14H10O4
Formula Weight: 242.2
CAS Number: 56317-21-6
Notes: A polyphenol with diverse biological activities; inhibits PDE4D2 and PDE4B2 (IC50s = 1.9 and 4.5 µM, respectively); induces cell death in P388 cells (IC50 = 24.8 µM); inhibits IL-1β-induced increases in the levels of phosphorylated ERK and JNK in A549 cells at 30 or 50 µM; inhibits LPS-induced increases in NO and iNOS levels in MH-S macrophages at 50 and 60 µM, respectively; inhibits LPS-induced increases in the number of neutrophils, alveolar macrophages, and dendritic cells in BALF, the thickness of alveolar walls, and the levels of NF-κB in the lungs in a rat model of acute lung injury at 60 mg/kg