Clone Number: IPO-24
Immunogen: spleen cells of a patient with hairy cell leukemia
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: IPO-24 reacts with CD37, a B lineage restricted antigen, strongly expressed throughout B-cell ontogeny from pre B-cell until plasmablasts. Plasma cells are negative. IPO-24 reacts with human B-cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T-cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are negative. IPO-24 stains Bcell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrophils, macrophages, thymocytes and dendritic reticulum cells are negative.
Applications: FC, IHC-fr, IF
References: G. Moldenhauer G. et al., CD37 Workshop Panel report in: Schlossman et al., Leucocyte Typing V, B9, 544-545, (1995)/Sidorenko S.P. et al., J. Tumor Marker Oncology 5: 232 (1990)/Sidorenko S.P. et al., Haemat. Transfusiol. 35 N4: 19-22 (1990)
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