Background: Predicted to enable death receptor binding activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of cytokine production. Predicted to act upstream of or within activation of NF-kappaB-inducing kinase activity. Predicted to be located in plasma membrane. Used to study inflammatory bowel disease 16. Orthologous to human TNFSF15 (TNF superfamily member 15). [provided by Alliance of Genome Resources, Apr 2022]
Description: Recombinant mouse TNFSF15 protein with N-terminal human Fc tag
Molecular Weight: The protein has a predicted molecular mass of 47.6 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mTNFSF15 is approximately 55-70 kDa due to glycosylation.
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: N-Human Fc Tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target: TNFSF15
Uniprot ID: Q5UBV8
Usage: Research use only
Molecular Characterization: hFc(Glu99-Ala330) Mouse TNFSF15(Ala61-Leu252)
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.