MRK-623, CAS 461449-78-5

Product Description: MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect[1].

Applications: Neuroscience-Neuromodulation

Formula: C20H17FN4O

References: [1]Simon C Goodacre, et al. Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders. J Med Chem. 2006 Jan 12;49(1):35-8.

CAS Number: 461449-78-5

Molecular Weight: 348.37

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: GABA Receptor

• SKU: MEXHY-123840-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123840-50
• Package Unit: 50 mg
• Quantity Unit: STK