MRT-81, CAS 1263132-08-6

Product Description: MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancer[1].

Applications: Cancer-programmed cell death

Formula: C31H29N3O5S

References: [1]Solinas A, et al. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. J Med Chem. 2012 Feb 23;55(4):1559-71.

CAS Number: 1263132-08-6

Molecular Weight: 555.64

Compound Purity: 99.85

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Smo

• SKU: MEXHY-145387-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145387-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK