MRTX-1257, CAS 2206736-04-9

Product Description: MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells[1].

Applications: Cancer-Kinase/protease

Formula: C33H39N7O2

References: [1]Matthew et al. Structure-Based Drug Discovery of MRTX1257, a Selective, Covalent KRAS G12C Inhibitor with Oral Activity in Animal Models of Cancer.

CAS Number: 2206736-04-9

Molecular Weight: 565.71

Compound Purity: 99.14

Research Area: Cancer

Solubility: DMSO : 55 mg/mL (ultrasonic)

Target: Ras

• SKU: MEXHY-114436-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-114436-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK