MS023, CAS 1831110-54-3

Product Description: MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1].

Applications: Cancer-programmed cell death

Formula: C17H25N3O

References: [1]Eram MS, et al. A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. ACS Chem Biol. 2016 Mar 18;11(3):772-81./[2]Yinghui Zhu, et al. Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia. Blood. 2019 Oct 10;134(15):1257-1268.

CAS Number: 1831110-54-3

Molecular Weight: 287.40

Compound Purity: 99.73

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Histone Methyltransferase

• SKU: MEXHY-19615-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19615-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK