Product Description: MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8.
Applications: Cancer-Kinase/protease
Formula: C18H17ClN4O
References: [1]Czodrowski P, et al. Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening. J Med Chem. 2016 Oct 27;59(20):9337-9349.
CAS Number: 1883423-59-3
Molecular Weight: 340.81
Compound Purity: 99.62
Research Area: Cancer
Solubility: DMSO : 110 mg/mL (ultrasonic)
Target: CDK