Application Note: WB: 1:300-1:5000. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): 10mM TBS, 1% BSA, 50% Glycerol, 0.02% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13043
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human MST1 (385-487 aa).
Purification: Purified by Protein A
Conjugation: Unconjugated
Full Name: serine/threonine kinase 4
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