Mubritinib, CAS 366017-09-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole

Purity: ≥98%

Formula Markup: C25H23F3N4O2

Formula Weight: 468.5

CAS Number: 366017-09-6

Notes: Mubritinib is a selective inhibitor of the human epidermal growth factor receptor 2 (HER2), inhibiting HER2 phosphorylation with an IC50 value of 6 nM.{21787} It is without effect on EGFR, FGFR, PDGFR, JAK1, Src, and Blk (IC50 > 25 μM).{21787} Mubritinib inhibits the proliferation of breast, bladder, kidney, and prostate cancer cells in vitro and in vivo.{21787,21788}

• SKU: CAY12096-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 12096-100
• Package Unit: 100 mg
• Quantity Unit: STK