Product Description: Mubritinib (TAK-165) is a potent and selective EGFR2/HER2 inhibitor with an IC50 of 6 nM.
Applications: Cancer-Kinase/protease
Formula: C25H23F3N4O2
References: [1]Nagasawa J, et al. Novel HER2 selective tyrosine kinase inhibitor, TAK-165, inhibits bladder, kidney and androgen-independent prostate cancer in vitro and in vivo. Int J Urol. 2006 May;13(5):587-92.
CAS Number: 366017-09-6
Molecular Weight: 468.47
Compound Purity: 99.91
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: EGFR