MyD88 antibody (HL3601)

Clone Name: HL3601

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Uniprot ID: Q99836

Antigen Species: Human

Immunogen: Recombinant fragment of human MyD88.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: MYD88 innate immune signal transduction adaptor

• SKU: GTX641576-S-25
• Manufacturer: GeneTex
• Manufacturer SKU: GTX641576-S-25
• Package Unit: 25 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Western Blotting
• Isotype: IgG
• Human Gene ID: 4615
• Host: Rabbit
• Conjugate: Unconjugated