MyD88 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89605.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Region Sequence: C-IKYKAMKKEFP

Full Name: myeloid differentiation primary response 88

• SKU: GTX89605-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89605-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 4615