Application Note: WB: 2-6μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 243
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89296-PEP).
Specificity/Sensitivity: This antibody is expected to recognise both reported isoforms (NP_004136.2; NP_001123537.1).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Uniprot ID: Q13459
Antigen Species: Human
Immunogen: Peptide with sequence C-KNDFEPVKQSKAQ, from the internal region of the protein sequence according to NP_004136.2; NP_001123537.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: myosin IXB
English
Deutsch
