MYO9B blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89296.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Region Sequence: C-KNDFEPVKQSKAQ

Full Name: myosin IXB

• SKU: GTX89296-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89296-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 4650