Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-acetyl-aspartic acid
Purity: ≥98%
Formula Markup: C6H9NO5
Formula Weight: 175.1
CAS Number: 2545-40-6
Notes: N-Acetyl-DL-aspartic acid is an acetylated form of L-aspartic acid.{63202} It is formed from L-aspartate and acetyl-CoA (Item No. 16160) by L-aspartate N-acetyltransferase (Asp-NAT) in neuronal mitochondria.{63203} N-Acetyl-DL-aspartic acid is hydrolyzed to L-aspartate and acetate by aspartoacylase (ASPA), which is expressed by oligodendrocytes. N-Acetyl-DL-aspartic acid levels are increased in the brain of patients with Canavan disease, an autosomal recessive disorder caused by loss-of-function ASPA mutations and characterized by cognitive and motor impairments.{63204,63203,63202}