(±)-N-desmethyl Venlafaxine (hydrochloride), CAS 93413-90-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol, monohydrochloride

Purity: ≥95%

Formula Markup: C16H25NO2 / HCl

Formula Weight: 299.8

CAS Number: 93413-90-2

Notes: (±)-N-desmethyl Venlafaxine is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine.{65180} It is formed from venlafaxine by the cytochrome P450 (CYP) isoform CYP3A4.{32155} (±)-N-desmethyl Venlafaxine inhibits norepinephrine and serotonin reuptake in rat synaptosome preparations (IC50s = 4.7 and 1.6 µM, respectively).{65180} In vivo, (±)-N-desmethyl venlafaxine reverses reserpine-induced hypothermia in mice with a minimum effective dose (MED) of 10 mg/kg.

• SKU: CAY35403-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35403-25
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe