NAcM-OPT, CAS 2089293-61-6

Product Description: NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction[1].

Applications: Cancer-programmed cell death

Formula: C23H29Cl2N3O

References: [1]Hammill JT, et al. Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. J Med Chem. 2018 Apr 12;61(7):2694-2706.

CAS Number: 2089293-61-6

Molecular Weight: 434.40

Compound Purity: 99.65

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: E1/E2/E3 Enzyme;NEDD8-activating Enzyme

• SKU: MEXHY-111505-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111505-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK