Product Description: Narasin is a cationic ionophore antibiotic and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin has antimicrobial, antiviral anticancer activity. Narasin inhibits tumor metastasis and growth of ERα‑positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL‑6/STAT3 signaling pathways[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C43H72O11
References: [1]Ghada Bouguerra, et al. Stimulation of Eryptosis by Narasin. Cell Physiol Biochem. 2015;37(5):1807-16./[2]Low JS, et al. Narasin, a novel antiviral compound that blocks dengue virus protein expression. Antivir Ther. 2011;16(8):1203-18./[3]Chen J, et al. Narasin inhibits tumor metastasis and growth of ERα‑positive breast cancer cells by inactivation of the TGF‑β/SMAD3 and IL‑6/STAT3 signaling pathways. Mol Med Rep. 2020 Dec;22(6):5113-5124.
CAS Number: 55134-13-9
Molecular Weight: 765.03
Compound Purity: 98.0
Research Area: Cancer; Infection
Solubility: DMSO : 12.5 mg/mL (ultrasonic)
Target: Antibiotic;Apoptosis;Bacterial;NF-κB;Parasite
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