Nargenicin A1, CAS 70695-02-2

Product Description: Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia[1].

Applications: COVID-19-immunoregulation

Formula: C28H37NO8

References: [1]Da Hye Kwon, et al. Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway. EXCLI J. 2021 May 28;20:968-982./[2]Dhakal D, et al. Characterization of Tailoring Steps of Nargenicin A1 Biosynthesis Reveals a Novel Analogue with Anticancer Activities. ACS Chem Biol. 2020 Jun 19;15(6):1370-1380.

CAS Number: 70695-02-2

Molecular Weight: 515.60

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Antibiotic;Apoptosis;Bacterial;NF-κB

• SKU: MEXHY-123121-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123121-1
• Package Unit: 1 mg
• Quantity Unit: STK