Nav1.1 activator 1, CAS 2332897-85-3

Product Description: Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 μM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6[1].

Applications: Neuroscience-Neurodegeneration

Formula: C24H23F3N4O

References: [1]Miyazaki T, et al. Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Nav1.1 activators. Bioorg Med Chem Lett. 2019 Mar 15;29(6):815-820.

CAS Number: 2332897-85-3

Molecular Weight: 440.46

Compound Purity: 99.89

Research Area: Neurological Disease

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Sodium Channel

• SKU: MEXHY-126429-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-126429-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK