Nav1.5 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89500.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Region Sequence: C-ETDDQSPEKIN

Full Name: sodium voltage-gated channel alpha subunit 5

• SKU: GTX89500-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89500-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 6331