NCGC00029283, CAS 714240-31-0

Product Description: NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively[1].

Applications: Cancer-programmed cell death

Formula: C18H12FN3O3

References: [1]Joshua A Sommers, et al. A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN). PLoS One. 2019 Jan 9;14(1):e0210525.

CAS Number: 714240-31-0

Molecular Weight: 337.30

Compound Purity: 98.88

Research Area: Cancer

Solubility: DMSO : 6.94 mg/mL (ultrasonic;warming;heat to 60°C)

Target: DNA/RNA Synthesis

• SKU: MEXHY-128712-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128712-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK