Nedometinib, CAS 2252314-46-6

Shelf life (days): 1460

Info: A MEK1 inhibitor (IC50 = 135 nM); selective for MEK1 over a panel of 44 receptors, ion channels, and enzymes at 10 µM, as well as a panel of an additional 150 kinases; decreases phosphorylation of ERK in malignant peripheral nerve sheath tumor cells at 0.1-10 µM; topical application reduces the total number of tumors in a mouse model of UV radiation-induced cutaneous squamous cell carcinoma

Formulation: A solid

Formal Name: 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

Purity: ≥98%

Formula Markup: C17H16FIN4O3

Formula Weight: 470.2

CAS Number: 2252314-46-6

• SKU: CAY40465-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40465-5
• Package Unit: 5 mg
• Quantity Unit: STK