Clone Name: 19R23
Application Note: WB: 1:500 - 1:1000. ELISA: 1:1000 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody recognizes human NRG1-beta1/HRG1-beta1 EFG domain by ELISA and WB.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
Uniprot ID: Q02297/Q15491
Antigen Species: Human
Immunogen: Recombinant Human NRG1-β1/HRG1-β1
Purification: Protein G purified
Conjugation: Unconjugated