Description: Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders, and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary.
Formula: C80H122F3N21O22
Molecular Weight: 1786,98
References: Feng YP, Wang J, Dong YL, Wang YY, Li YQ. The roles of neurotensin and its analogues in pain. Curr Pharm Des. 2015;21(7):840-8. doi: 10.2174/1381612820666141027124915.
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