Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Purity: ≥98%
Formula Markup: C15H14N4O
Formula Weight: 266.3
CAS Number: 129618-40-2
Notes: Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).{22819} It binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM). Nevirapine prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection.{49140} Formulations containing nevirapine have been used in combination therapy for the treatment of HIV-1 infection.