NH125, CAS 278603-08-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide

Purity: ≥95%

Formula Markup: C27H45IN2

Formula Weight: 524.6

CAS Number: 278603-08-0

Notes: NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria.{16459} In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM.{16460} NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM.{16458} In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50 = 7.5 µM), protein kinase A (IC50 = 80 µM), and calmodulin-dependent kinase II (IC50 = 100 µM).{16458}

• SKU: CAY10011250-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10011250-5
• Package Unit: 5 mg
• Quantity Unit: STK