NI-57, CAS 1883548-89-7

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CAS Number: 1883548-89-7

Description: NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI-57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI-57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.

Format: Solid

Storage Stability: At least 6 months at -20°C. 

Warnings: Avoid freeze/thaw cycles

Biosafety Level: Not applicable (BSL-1)

• SKU: BPS82069
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 82069
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK